FGF21 protein (30R-AF039)

Purified recombinant Human FGF21 protein

Synonyms FGFL protein, FGF 21, FGF-21, FGF21, FGF-21 protein, Fibroblast Growth Factor-21 protein, FGF 21 protein, FGF-21 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of FGF21 protein corresponding to amino acids MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS.
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 19.5 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity FGF-21, in the absence of betaKlotho, shows weak activity of thymidine uptake by BaF3 cells expressing FGF receptors.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance FGF21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes.

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Availability: In stock

Price: €211.69
Size: 20 ug
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