Fibrinopeptide A antibody (70R-10619)
Affinity purified sheep polyclonal Fibrinopeptide A antibody
Overview
Overview
| Synonyms | Polyclonal Fibrinopeptide A antibody, Anti-Fibrinopeptide A antibody |
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| Applications | User optimized |
| Immunogen | Fibrinopeptide A antibody was raised in sheep using Synthetic Fibrinopeptide A 1-16 conjugated to carrier as the immunogen. |
Specifications
| Host | Sheep |
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| Isotype | IgG |
| Method of Purification | Fibrinopeptide A antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50% (v/v) glycerol. |
Storage & Safety
| Storage | Store at -10 to -20 deg C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. |
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General Information
| Biological Significance | The conversion of fibrinogen to fibrin occurs in several steps. First, thrombin cleaves the N-terminus of the fibrinogen alpha and beta chains to fibrinopeptide A and B respectively. The resulting fibrin monomers polymerize end to end to from protofibrils which in turn associate laterally to form fibrin fibers. In a final step, the fibrin fibers associate to form the fibrin gel. |
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