Filamin A antibody (10-F82A)
Mouse monoclonal Filamin A antibody
Overview
Overview
| Synonyms | Monoclonal Filamin A antibody, Anti-Filamin A antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | Bovine |
| Applications | IF, IP, WB |
| Immunogen | Filamin A antibody was raised in mouse using human platelet protein as the immunogen. |
Images
Immunohistochemical staining using Filamin A antibody (10-F82A)
Mouse anti-Filamin antibody staining of MeOH fixed fibroblast.
Specifications
| Host | Mouse |
|---|---|
| Clone | M95041 |
| Isotype | IgG1 |
| Form & Buffer | Ascites fluid. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | WB: 1:250-1:1,000, IF: 1:50-1:200 |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles |
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General Information
| Biological Significance | Filamin is a structural protein that forms flexible cross-links between two actin filaments. Filamin is a homodimer of polypeptide chains each joined to the other at one end with an actin binding site ath the other. It is present in smooth muscle, fibroblasts, platelets and lymphocytes. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers. |
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