Filamin B antibody (70R-12564)
Affinity purified Rabbit polyclonal Filamin B antibody
Overview
Overview
| Synonyms | Polyclonal Filamin B antibody, Anti-Filamin B antibody, filamin-3 antibody, SCT antibody, thyroid autoantigen antibody, ABP-280 antibody, LRS1 antibody, FLNB antibody, Larsen syndrome 1 (autosomal dominant) antibody, actin binding protein 278 antibody, ABP-280 homolog antibody, AOI antibody, actin-binding-like protein antibody, beta-filamin antibody, TAP antibody, ABP-278 antibody, DKFZp686A1668 antibody, FH1 antibody, DKFZp686O033 antibody, filamin homolog 1 antibody, FLN1L antibody, filamin-B antibody, TABP antibody |
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| Cross Reactivity | Human, Mouse |
| Applications | ICC, IF, WB |
| Immunogen | Filamin B antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 30 and 269 of Filamin B |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | Filamin B antibody was purified by Protein A chromatography |
| Molecular Weight | 278 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 1X PBS, 1% BSA, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 10 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:1000, ICC:1:100-1:1000, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. |
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