Filamin protein (Chicken) (30R-AF016)
Highly purified Filamin protein
Overview
Overview
| Species | Chicken |
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| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Chicken gizzard |
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| Form & Buffer | Supplied as a lyophilized powder. Reconstitute with 250 ul of Laemmli buffer. Final solution contains 20mM Tris/acetate pH 7.6, 20 mM NaCl, 0.1mM EDTA, 2mM DTT, and 20mM NaCl. |
Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers. |
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