FKBP12 antibody (70R-11962)
Rabbit polyclonal FKBP12 antibody
Overview
Overview
| Synonyms | Polyclonal FKBP12 antibody, anti-FKBP12 antibody, FKBP-12 antibody, FKBP1A antibody, FKBP1 antibody, FKBP12, FKBP-12, FKBP 12, FKBP 12 antibody |
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| Cross Reactivity | Human, Mouse, Rat |
| Applications | IHC, IP, WB |
| Immunogen | FKBP12 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 10 of mouse FKBP12 as the immunogen. |
| Assay Information | FKBP12 Blocking Peptide, catalog no. 33R-10847, is also available for use as a blocking control in assays to test for specificity of this FKBP12 antibody |
Images
Western Blot analysis using FKBP12 antibody (70R-11962)
Western blot analysis of FKBP12 expression in rat kidney tissue lysate.
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | FKBP12 antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
| Concentration | 500 ug/ml |
Usage & Assay Information
| Usage Recommendations | IP: 2-10 ug/ml, IHC: 2-10 ug/ml, WB: 0.5-4 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway. |
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