FKBP12 antibody (70R-11962)

Rabbit polyclonal FKBP12 antibody

Synonyms Polyclonal FKBP12 antibody, anti-FKBP12 antibody, FKBP-12 antibody, FKBP1A antibody, FKBP1 antibody, FKBP12, FKBP-12, FKBP 12, FKBP 12 antibody
Cross Reactivity Human, Mouse, Rat
Applications IHC, IP, WB
Immunogen FKBP12 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 10 of mouse FKBP12 as the immunogen.
Assay Information FKBP12 Blocking Peptide, catalog no. 33R-10847, is also available for use as a blocking control in assays to test for specificity of this FKBP12 antibody

Images

Western Blot analysis using FKBP12 antibody (70R-11962)

Western blot analysis of FKBP12 expression in rat kidney tissue lysate.

Specifications

Host Rabbit
Isotype IgG
Method of Purification FKBP12 antibody was purified by affinity chromatography
Form & Buffer Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations IP: 2-10 ug/ml, IHC: 2-10 ug/ml, WB: 0.5-4 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.

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Images

  • <div><font face=Calibri size=2>Western Blot analysis using FKBP12 antibody (70R-11962)</font></div>     | Western blot analysis of FKBP12 expression in rat kidney tissue lysate.

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