FKBP1A protein (80R-4222)
Recombinant Mouse FKBP1A protein with His tag
Overview
Overview
| Synonyms | Mouse FKBP1A protein, Recombinant FKBP1A protein, Peptidyl-prolyl cis-trans isomerase FKBP1A protein, 12kDa protein, Fkbp protein, Fkbp1 protein, FKBP12 protein, FKBP12-T1 protein, FKBP12-T2 protein, mFKBP1 protein, mFKBP12 protein |
|---|---|
| Species | Mouse |
| Protein Type | Recombinant |
| Applications | Control, SDS-PAGE |
Images
Coomassie blue stained SDS-PAGE showing analysis of FKBP1A protein(80R-4222)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 1-108 amino acids of Mouse FKBP1A protein: MGSSHHHHHH SSGLVPRGSH MGSHMGVQVE TISPGDGRTF PKRGQTCVVH YTGMLEDGKK FDSSRDRNKP FKFTLGKQEV IRGWEEGVAQ MSVGQRAKLI ISSDYAYGAT GHPGIIPPHA TLVFDVELLK LE |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Molecular Weight | 14.4 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in PBS (pH 7.4) containing 20% glycerol and 1mM DTT |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term. For long term storage, aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles. |
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General Information
| Biological Significance | Fkbp1a also known as peptidyl-prolyl cis-trans isomerase FKBP1A belongs to the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Fkbp1a also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1, 4, 5-trisphosphate receptor. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. Recombinant mouse Fkbp1a, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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