FKBP52 antibody (70R-13537)

Affinity purified Rabbit polyclonal FKBP52 antibody

Synonyms Polyclonal FKBP52 antibody, Anti-FKBP52 antibody, FKBP 52 antibody, FKBP52, FK506-binding protein 4 (59kD) antibody, HBI antibody, FKBP-52, FKBP51 antibody, p52 antibody, FKBP-52 antibody, peptidylprolyl cis-trans isomerase antibody, FKBP 52, T-cell FK506-binding protein 59kD antibody, FKBP52 antibody, FKBP59 antibody, FKBP4 antibody, Hsp56 antibody, PPIase antibody
Cross Reactivity Human, Mouse
Applications ICC, IF, IHC-P, WB

Images

Western blot analysis using FKBP52 antibody (70R-13537)

Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 10 % SDS PAGE gel and FKBP52 antibody at a dilution of 1:1000

Specifications

Host Rabbit
Isotype IgG
Method of Purification FKBP52 antibody was purified by antigen-affinity chromatography
Molecular Weight 52 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 0.99 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:1000-1:10000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A, but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.

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Images

  • <div><font face=Calibri size=2>Western blot analysis using FKBP52 antibody (70R-13537)</font></div>     | Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 10 % SDS PAGE gel and FKBP52 antibody at a dilution of 1:1000
  • <div><font face=Calibri size=2>Western blot analysis using FKBP52 antibody (70R-13537)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: H1299) using a 10 % SDS PAGE gel and FKBP52 antibody at a dilution of 1:5000
  • <div><font face=Calibri size=2>Immunofluorescent staining using FKBP52 antibody (70R-13537)</font></div>     | Immunofluorescence analysis of paraformaldehyde-fixed A431, using FKBP52 antibody at 1:200 dilution.
  • <div><font face=Calibri size=2>Immunohistochemical staining using FKBP52 antibody (70R-13537)</font></div>     | Immunohistochemical staining of paraffin-embedded Cal27 xenograft using FKBP52 antibody at a dilution of 1:500

Availability: In stock

Price: €395.09
Size: 100 ul
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