FLASH antibody (70R-FR017)

Affinity purified Rabbit polyclonal FLASH antibody

Synonyms Polyclonal FLASH antibody, Anti-FLASH antibody
Cross Reactivity To be determined by end-user
Applications WB
Immunogen FLASH antibody was raised in rabbit using N terminus of the FLASH protein as the immunogen.

Specifications

Host Rabbit
Isotype IgG
Method of Purification FLASH antibody was purified by affinity chromatography.
Form & Buffer Affinity purified IgG supplied in PBS with 0.02% NaN3.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance FLASH, contains a motif with oligomerizing activity whose sequence is similar to that of the Caenorhabditis elegans protein CED-4, and another domain (DRD domain) that interacts with a death-effector domain in caspase-8 or in the adapter protein. FLASH is likely a component of the DISC signalling complex and is necessary for the activation of caspase-8 in Fas-mediated apoptosis.

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Availability: In stock

Price: €235.21
Size: 100 ug
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