FMO1 antibody (70R-12787)
Affinity purified Rabbit polyclonal FMO1 antibody
Overview
Overview
| Synonyms | Polyclonal FMO1 antibody, Anti-FMO1 antibody, dimethylaniline oxidase 1 antibody, FMO-1 antibody, FMO-1, FMO 1, FMO1 antibody, fetal hepatic flavin-containing monooxygenase 1 antibody, FMO 1 antibody, dimethylaniline monooxygenase [N-oxide-forming] 1 antibody, FMO1 |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | FMO1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 437 of FMO1 |
Images
Western blot analysis using FMO1 antibody (70R-12787)
Western blot analysis of 30 ug whole cell lysate (A:Hep G2; B:Raji) using a 7.5 % SDS PAGE gel and FMO1 antibody at a dilution of 1:1000
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | FMO1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 60 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. |
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