FSCN1 antibody (10R-11438)
Mouse Monoclonal FSCN1 antibody
Overview
Overview
| Synonyms | Monoclonal FSCN1 antibody, Anti-FSCN1 antibody, Fascin antibody, FAN1 antibody, HSN antibody, SNL antibody, Fascin |
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| Applications | ELISA, FC, ICC, WB |
| Immunogen | FSCN1 antibody was raised in Mouse using recombinant human FSCN1 (1-493aa), purified from E. coli, as the immunogen |
Specifications
| Host | Mouse |
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| Clone | AT13D2 |
| Isotype | IgG2b kappa |
| Method of Purification | FSCN1 antibody was purified by protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage or -20 deg C for long term storage |
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General Information
| Biological Significance | FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells. |
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