FXYD5 antibody (70R-1683)

Rabbit polyclonal FXYD5 antibody raised against the middle region of FXYD5

Synonyms Polyclonal FXYD5 antibody, Anti-FXYD5 antibody, KCT1 antibody, PRO6241 antibody, IWU1 antibody, dysad antibody, HSPC113 antibody, Fsxyd5, IWU-1 antibody, Fsxyd 5 antibody, Fxyd Domain Containing Ion Transport Regulator 5 antibody, Fsxyd 5, Fsxyd-5 antibody, RIC antibody, OIT2 antibody, Fsxyd-5
Specificity FXYD5 antibody was raised against the middle region of FXYD5
Cross Reactivity Human
Applications WB
Immunogen FXYD5 antibody was raised using the middle region of FXYD5 corresponding to a region with amino acids DETPQPQTQTQQLEGTDGPLVTDPETHKSTKAAHPTDDTTTLSERPSPST
Assay Information FXYD5 Blocking Peptide, catalog no. 33R-1922, is also available for use as a blocking control in assays to test for specificity of this FXYD5 antibody

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 20 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of FXYD5 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1.25 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.

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Availability: In stock

Price: €258.73
Size: 100 ug
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