Galectin 1 protein (30R-1385)
Purified recombinant Human Galectin 1 protein
|Synonyms||Galectin 1 protein, Galectin1 protein, LGALS 1 protein, Beta galactoside binding lectin protein, GBP protein, Galectin1, S Lac lectin 1., Galectin protein, HPL protein, HBL protein, lactose-binding lectin 1 protein, MAPK activating protein MP12 protein, Putative MAPK activating protein MP12 protein, S-Lac lectin1 protein, GAL1 protein, DKFZp686E23103 protein, Galectin 1, Lactose binding lectin 1 protein, galaptin protein, Galectin-1, LGALS1 protein, GBP protein, Galectin-1 protein, Lectin galactoside binding soluble 1 protein, Beta galactoside binding lectin L 14 I protein, 14 kDa lectin protein|
Coomassie Blue stained SDS-PAGE of Galectin 1 protein (30R-1385)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-135 amino acids: MACGLVASNL NLKPGECLRV RGEVAPDAKS FVLNLGKDSN NLCLHFNPRF NAHGDANTIV CNSKDGGAWG TEQREAVFPF QPGSVAEVCI TFDQANLTVK LPDGYEFKFP NRLNLEAINY MAADGDFKIK CVAFD|
|Grade & Purity||> 90% pure|
|Molecular Weight||14.7 kDa (135aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl, pH 7.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||Galectin-1 is a member of the beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This protein is an autocrine negative growth factor that regulates cell proliferation. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes, thus Galectin-1 has immunosuppressive and anti-inflammatory properties. Galectin-1 also regulates tumor angiogenesis and is a target for angiostatic cancer therapy. Recombinant human Galectin-1 was expressed in E. coli and purified by using conventional chromatography|
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