Galectin 3 protein (His tag) (80R-1213)

Purified recombinant Human Galectin3 protein

Synonyms Galactoside-binding protein protein, galactose binding protein, MAC2. protein, Galectin -3, Laminin-binding protein protein, LGALS2 protein, L 34 protein, Galectin 3 protein, soluble 3 protein, L-34 galactoside-binding lectin protein, Lectin protein, LGALS3 protein, included protein, Galectin-3 protein, Galectin 3 internal gene protein, L31 protein, MAC 2 protein protein, Carbohydrate binding protein 35 protein, Galectin 3, L 31 protein, GBP protein, Galectin3 protein, IgE binding protein protein, IgE-binding protein protein, 35 kDa lectin protein, CBP35 protein, Galectin 3, Lectin L-29 protein, Galectin -3 protein, GALBP protein, GALIG protein, Mac-2 protein, Macrophage galactose-specific lectin protein, Galactose-specific lectin 3 protein, MGC105387., GAL3 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Galectin3 protein (His tag) (80R-1213)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-250 amino acids: MGSSHHHHHH SSGLVPRGSH MADNFSLHDA LSGSGNPNPQ GWPGAWGNQP AGAGGYPGAS YPGAYPGQAP PGAYPGQAPP GAYPGAPGAY PGAPAPGVYP GPPSGPGAYP SSGQPSATGA YPATGPYGAP AGPLIVPYNL PLPGGVVPRM LITILGTVKP NANRIALDFQ RGNDVAFHFN PRFNENNRRV IVCNTKLDNN WGREERQSVF PFESGKPFKI QVLVEPDHFK VAVNDAHLLQ YNHRVKKLNE ISKLGISGDI DLTSASYTMI
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 28.3 kDa (270aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 1mM DTT.
Concentration 0.5 mg/ml

Usage & Assay Information

Bioactivity The ED50 for this effect is 10-20 ug/ml. Measured by its ability to agglutinate human red blood cells.

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Galectin-3 is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. Galectin-3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant Galectin-3 protein was expressed in E. coli and purified by using conventional chromatography techniques.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Coomassie Blue stained SDS-PAGE of Galectin3 protein (His tag) (80R-1213) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €206.99
Size: 100 ug
OR
Shipping
View Our Distributors