Store at 4 deg C for up to 1 month. For long term storage, aliquot and store at -20 to -80 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information
This product contains sodium azide which is hazardous
General Information
Biological Significance
GATA3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA-3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells. GATA-3 was shown to be required for the luminal A type of breast cancer, intertwined in pathways with ER alpha. However, it is also hypothesised that GATA-3 may play tissue specific roles.