GATA3 antibody (10R-2951)

Rat monoclonal GATA3 antibody

Synonyms Monoclonal GATA3 antibody, Anti-GATA3 antibody, Trans-acting T-cell specific transcription factor antibody, GATA 3 antibody, GATA 3, GATA-3 antibody, GATA-3, GATA3, GATA 3 antibody, GATA-3 antibody
Specificity Mouse
Applications IF, WB
Immunogen GATA3 antibody was raised in Rat using Mouse GATA-3 as the immunogen.

Specifications

Host Rat
Clone KT63
Isotype IgG2a
Method of Purification GATA3 antibody was purified by Protein G chromatography.
Form & Buffer Supplied in PBS containing 0.1% sodium azide as a preservative
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF: 1-10 ug/ml; WB: 0.1-1 ug/ml

Storage & Safety

Storage Store at 4 deg C for up to 1 month. For long term storage, aliquot and store at -20 to -80 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide which is hazardous

General Information

Biological Significance GATA3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA-3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells. GATA-3 was shown to be required for the luminal A type of breast cancer, intertwined in pathways with ER alpha. However, it is also hypothesised that GATA-3 may play tissue specific roles.

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Availability: In stock

Price: €190.59
Size: 100 ug
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