GBA antibody (70R-12566)
Affinity purified Rabbit polyclonal GBA antibody
Overview
Overview
| Synonyms | Polyclonal GBA antibody, Anti-GBA antibody, GBA1 antibody, acid beta-glucosidase antibody, D-glucosyl-N-acylsphingosine glucohydrolase antibody, GCB antibody, GLUC antibody, beta-glucocerebrosidase antibody, imiglucerase antibody, lysosomal glucocerebrosidase antibody, GBA antibody, glucosylceramidase antibody |
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| Cross Reactivity | Human |
| Applications | ICC, IF, IHC-P, WB |
| Immunogen | GBA antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 352 and 536 of GBA |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | GBA antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 60 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.82 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. |
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