GBA protein (80R-4290)

Purified Recombinant GBA protein (His tagged)

Synonyms GBA1 protein, GCB protein, GLUC protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis using GBA protein (His tag) (80R-4290)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 40-536 aa: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR VPMASCDFSI RTYTYADTPD DFQLHNFSLP EEDTKLKIPL IHRALQLAQR PVSLLASPWT SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA RYFVKFLDAY AEHKLQFWAV TAENEPSAGL LSGYPFQCLG FTPEHQRDFI ARDLGPTLAN STHHNVRLLM LDDQRLLLPH WAKVVLTDPE AAKYVHGIAV HWYLDFLAPA KATLGETHRL FPNTMLFASE ACVGSKFWEQ SVRLGSWDRG MQYSHSIITN LLYHVVGWTD WNLALNPEGG PNWVRNFVDS PIIVDITKDT FYKQPMFYHL GHFSKFIPEG SQRVGLVASQ KNDLDAVALM HPDGSAVVVV LNRSSKDVPL TIKDPAVGFL ETISPGYSIH TYLWRRQHHH HHH
Expression System Insect cells
Grade & Purity > 80% pure
Molecular Weight 50-70 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in PBS buffer (pH 7.4) containing 10% glycerol
Concentration 500 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeat freeze/thaw cycles
Endotoxin Levels < 1.0 EU per 1 microgram of protein

General Information

Biological Significance GBA, also known as glucosylceramidase isoform 1, is a lysosomal enzyme that presumably requires a signal peptide for transport across the membrane of the rough endoplasmic reticulum and glycosylation for transport into lysosomes. Gaucher disease is due to a deficiency in the activity of the enzyme glucocerebrosidase. Recombinant human GBA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

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Images

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SDS-PAGE analysis using GBA protein (His tag) (80R-4290)



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Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €306.75
Size: 50 ug
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