GDF10 protein (30R-1336)
Purified recombinant Human GDF10 protein
|Synonyms||GDF10, BMP3B protein, BMP-3b protein, GDF 10 protein, GDF-10, , GDF 10, BIP protein, BMP3B protein, GDF-10 protein, Growth differentiation factor 10 BMP 3b protein, GDF-10 protein, Bone inducing protein protein, Bone morphogenetic protein 3b [Precursor] protein, GDF 10 protein, Growth differentiation factor 10 protein|
Coomassie Blue stained SDS-PAGE of GDF10 protein (30R-1336)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||369-478 amino acids: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R|
|Grade & Purity||> 95% pure|
|Molecular Weight||12.5 kDa (111aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 10mM sodium citrate, pH 3.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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