GDF15 protein (His tag) (80R-4048)
Recombinant Mouse GDF15 protein (His tag)
Overview
Overview
| Synonyms | Growth/differentiation factor 15 precursor protein, MIC-1 protein, NAG-1 protein, SBF protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of GDF15 protein (His tag) (80R-4048)
Figure annotated with amount of protein analysed and % SDS PAGE gel.
Specifications
| Residues | 189-303 amino acids: MGSSHHHHHH SSGLVPRGSH MGSSAHAHPR DSCPLGPGRC CHLETVQATL EDLGWSDWVL SPRQLQLSMC VGECPHLYRS ANTHAQIKAR LHGLQPDKVP APCCVPSSYT PVVLMHRTDS GVSLQTYDDL VARGCHCA |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 90% pure |
| Molecular Weight | 14.9 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in 20mM phosphate buffer, pH 8.0 containing 10% glycerol. |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C short term. Aliquot and store at -70 deg C for long term and avoid repeated freeze thaw cycles |
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General Information
| Biological Significance | Growth/differentiation factor 15, also known as GDF15, is a member of the TGF superfamily. It has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. Recombinant mouse GDF15 fused to His-tag at N-terminus, was expressed in E.coli. |
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