GIT2 Blocking Peptide (33R-9761)
A synthetic peptide for use as a blocking control in assays to test for specificity of GIT2 antibody, catalog no. 70R-10347
Overview
Overview
| Synonyms | GIT2 control peptide, GIT2 antibody Blocking Peptide, Anti-GIT2 Blocking Peptide, G protein-coupled receptor kinase interacting ArfGAP 2 Blocking Peptide, CAT-2 Blocking Peptide, DKFZp686G01261 Blocking Peptide, KIAA0148 Blocking Peptide, MGC760 Blocking Peptide, GIT2, GIT-2, GIT 2, GIT-2 Blocking Peptide, GIT 2 Blocking Peptide |
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| Protein Type | Synthetic |
| Applications | IHC, WB |
Specifications
| Residues | VQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPE |
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| Molecular Weight | 83 kDa |
| Form & Buffer | Lyophilized powder. Add 100ul of distilled water for a final peptide concentration is 1 mg/ml. |
Storage & Safety
| Storage | Store at -20 deg C long term. Avoid repeat freeze-thaw cycles. |
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General Information
| Biological Significance | This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. |
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