Glutaredoxin I antibody (10R-7459)

Mouse monoclonal Glutaredoxin I antibody

Synonyms Monoclonal Glutaredoxin I antibody, Anti-Glutaredoxin I antibody, GRX antibody, Glutaredoxin antibody, GRX1 antibody, GLRX antibody, MGC117407 antibody, Thioltransferase antibody
Cross Reactivity Human
Applications IP
Immunogen Glutaredoxin I antibody was raised in Mouse using recombinant human protein purified from E.coli as the immunogen.

Images

Western blot analysis using Glutaredoxin I antibody (10R-7459)

Specifications

Host Mouse
Clone 28C3
Isotype IgG1 kappa
Method of Purification Glutaredoxin I antibody was purified by affinity chromatography.
Form & Buffer 0.15M Nacl, 0.01%BSA,and 50% glycerol. With 0.03% sodium azide added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IP 1-2ul/400ul lysates

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles..

General Information

Biological Significance Glutaredoxin (Grx), also known as thiol transferase, is a small heatstable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH (1). First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues (2). The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress (3).

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Images

  • Western blot analysis using Glutaredoxin I antibody (10R-7459) |

Availability: In stock

Price: €257.67
Size: 100 ul
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