Glutaredoxin2 protein (His tag) (80R-1227)

Purified recombinant Human Glutaredoxin2 protein

Synonyms Glutaredoxin 2 protein, CGI133, Glutaredoxin 2, GRX2 protein, GLRX2 protein, Glutaredoxin -2, Glutaredoxin 2, Glutaredoxin -2 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Glutaredoxin2 protein (His tag) (80R-1227)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 20-164 amino acids: MSAGWLDRAA GAAGAAAAAA SGMESNTSSS LENLATAPVN QIQETISDNC VVIFSKTSCS YCTMAKKLFH DMNVNYKVVE LDLLEYGNQF QDALYKMTGE RTVPRIFVNG TFIGGATDTH RLHKEGKLLP LVHQCYLKKS KRKEFQLEHH HHHH
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 17.0 kDa (154aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl Buffer, pH 8.0, containing 0.1mM PMSF and 10% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Glutaredoxin-2, as known as GRX2, is a multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase(GST) activity. This protein is localized both in the mitochondria and nucleus. It has anti-apoptotic activity by preventing cardiolipin oxidation and cytochrome c release. GRX2 exhibited 36% identity with GRX1 and had a disulfide active center containing the Cys-Ser-Tyr-Cys motif. Recombinant human Glutaredoxin 2, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of Glutaredoxin2 protein (His tag) (80R-1227) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €206.99
Size: 100 ug
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