Glutaredoxin3 protein (His tag) (80R-1315)
Purified recombinant Human Glutaredoxin3 protein
|Synonyms||Glutaredoxin3, thioredoxin-like 2 protein, Glutaredoxin 3, Glutaredoxin-3, PICOT protein, GLRX3 protein, glutaredoxin 3 protein, Glutaredoxin 3 protein, thioredoxin-like 2 protein, Thioredoxin-like protein 2 protein, Glutaredoxin-3 protein, , GLRX4 protein, GRX4 protein, glutaredoxin 4 protein, bA500G10.4 protein, TXNL2 protein, GRX3 protein|
Coomassie Blue stained SDS-PAGE of Glutaredoxin3 protein (His tag) (80R-1315)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-335 amino acids: MGSSHHHHHH SSGLVPRGSH MAAGAAEAAV AAVEEVGSAG QFEELLRLKA KSLLVVHFWA PWAPQCAQMN EVMAELAKEL PQVSFVKLEA EGVPEVSEKY EISSVPTFLF FKNSQKIDRL DGAHAPELTK KVQRHASSGS FLPSANEHLK EDLNLRLKKL THAAPCMLFM KGTPQEPRCG FSKQMVEILH KHNIQFSSFD IFSDEEVRQG LKAYSSWPTY PQLYVSGELI GGLDIIKELE ASEELDTICP KAPKLEERLK VLTNKASVML FMKGNKQEAK CGFSKQILEI LNSTGVEYET FDILEDEEVR QGLKAYSNWP TYPQLYVKGE LVGGLDIVKE LKENGELLPI LRGEN|
|Grade & Purity||> 95% pure|
|Molecular Weight||39.6 kDa (355aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Glutaredoxin(GRX), also known as thioltransferase, is a member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ. Recombinant human Glutaredoxin-3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
Sorry, but there are no references currently for this product.
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product