Glutaredoxin3 protein (His tag) (80R-1315)

Purified recombinant Human Glutaredoxin3 protein

Synonyms Glutaredoxin3, thioredoxin-like 2 protein, Glutaredoxin 3, Glutaredoxin-3, PICOT protein, GLRX3 protein, glutaredoxin 3 protein, Glutaredoxin 3 protein, thioredoxin-like 2 protein, Thioredoxin-like protein 2 protein, Glutaredoxin-3 protein, , GLRX4 protein, GRX4 protein, glutaredoxin 4 protein, bA500G10.4 protein, TXNL2 protein, GRX3 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Glutaredoxin3 protein (His tag) (80R-1315)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-335 amino acids: MGSSHHHHHH SSGLVPRGSH MAAGAAEAAV AAVEEVGSAG QFEELLRLKA KSLLVVHFWA PWAPQCAQMN EVMAELAKEL PQVSFVKLEA EGVPEVSEKY EISSVPTFLF FKNSQKIDRL DGAHAPELTK KVQRHASSGS FLPSANEHLK EDLNLRLKKL THAAPCMLFM KGTPQEPRCG FSKQMVEILH KHNIQFSSFD IFSDEEVRQG LKAYSSWPTY PQLYVSGELI GGLDIIKELE ASEELDTICP KAPKLEERLK VLTNKASVML FMKGNKQEAK CGFSKQILEI LNSTGVEYET FDILEDEEVR QGLKAYSNWP TYPQLYVKGE LVGGLDIVKE LKENGELLPI LRGEN
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 39.6 kDa (355aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 1mM DTT.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Glutaredoxin(GRX), also known as thioltransferase, is a member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ. Recombinant human Glutaredoxin-3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of Glutaredoxin3 protein (His tag) (80R-1315) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €206.99
Size: 100 ug
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