GNAS antibody (70R-12940)
Affinity purified Rabbit polyclonal GNAS antibody
Overview
Overview
| Synonyms | Polyclonal GNAS antibody, Anti-GNAS antibody, GSA antibody, adenylate cyclase-stimulating G alpha protein antibody, GPSA antibody, PHP1A antibody, NESP antibody, PHP1B antibody, POH antibody, protein ALEX antibody, GNAS antibody, MGC33735 antibody, GSP antibody, AHO antibody, PHP1C antibody, GNAS1 antibody, guanine nucleotide binding protein (G protein) alpha stimulating activity polypeptide 1 antibody, C20orf45 antibody, guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody |
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| Cross Reactivity | Human, Mouse |
| Applications | IHC-P, WB |
| Immunogen | GNAS antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 716 and 998 of GNAS |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | GNAS antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 111 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.78 mg/ml |
Usage & Assay Information
| Usage Recommendations | IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contains a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. |
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