Goat anti Human IgM Fc (41R-1106)
Goat anti Human IgMsecondary antibody (mu chain specific)
Overview
Overview
| Synonyms | Goat anti-Human Immunoglobulin M Fc fragment antibody |
|---|---|
| Specificity | Specific for Human IgM |
| Cross Reactivity | Does not react with Human IgG or IgA,or non-immunoglobulin serum proteins. Has minimum cross reactivity with bovine, horse, mouse, and rabbit serum proteins; but may cross-react with IgM from other species. |
| Applications | FC, IF, IHC |
| Immunogen | Purified human IgM Fc mu fragment |
Specifications
| Host | Goat |
|---|---|
| Isotype | IgG |
| Method of Purification | Goat anti Human IgM was purified by Affinity Chromatography |
| Form & Buffer | Supplied in 10 mM PO4, 150 mM NaCl, pH 7.6 with0.05% sodium azide. |
| Concentration | 1.5 mg/ml |
Usage & Assay Information
| Usage Recommendations | FC 1:50-1:200; IF 1:1000-1:10000 |
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Storage & Safety
| Storage | Store at 2-8 deg C |
|---|---|
| Biohazard Information | This product contains 0.05 % sodium azide as a preservative, appropriate care should be taken in handling. |
General Information
| Biological Significance | IgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/ml. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome. |
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