Goat anti Human IgM (mu chain) (biotin) (43R-1228)
Goat anti Human IgM (mu chain) secondary antibody (biotin)
Overview
Overview
| Synonyms | Goat anti Human Immunoglobulin M (mu chain) secondary antibody (biotin) |
|---|---|
| Specificity | This antibody reacts with heavy chains on human IgM (mu chain). |
| Cross Reactivity | No reactivity is observed to non-immunoglobulin human serum proteins light chains on all human immunoglobulins human IgA + IgG. |
| Applications | User optimized |
| Immunogen | Purified Human IgM |
Specifications
| Host | Goat |
|---|---|
| Source | Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian. |
| Grade & Purity | > 95% pure |
| Method of Purification | Affinity purified using solid phase Human IgM |
| Tag/Conjugate | Biotin |
| Form & Buffer | Clear, colorless liquid, containing 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, 1% (w/v) BSA and 0.05% (w/v) Sodium Azide. Protease/IgG free, pH 7.2. |
| Concentration | 1.0 mg/ml |
Usage & Assay Information
| Usage Recommendations | 1:2000-1:20,000 ELISA/WB, 1:500-1:5000 IHC |
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Storage & Safety
| Storage | Store at 2-8 deg C. |
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General Information
| Biological Significance | IgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/ml. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome. |
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