Goat IgG (Fc) (31C-CH0504)
Purified Goat IgG (Fc)
Overview
Overview
| Synonyms | Goat Immunoglobulin G (Fc) |
|---|---|
| Species | Goat |
| Applications | User optimized |
Specifications
| Method of Purification | Goat IgG (Fc) was purified by delipidation, salt fractionation and ion exchange chromatography followed by dialysis. |
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| Form & Buffer | Supplied as a liquid in 20 mM Potassium Phosphate and 150 mM Sodium Chloride, pH 7.2, with 0.01% Sodium Azide as a preservative. For extended storage, mix liquid with an equal volume of glycerol, aliquot contents, and store at -20°C. |
Storage & Safety
| Storage | Store at 4 deg C short term and at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | Immunoglobulin G (IgG) are antibody molecules. Each IgG is composed of four peptide chains - two heavy chains and two light chains. Each IgG has two antigen binding sites. Other Immunoglobulins may be described in terms of polymers with the IgG structure considered the monomer. The Fc regions of IgGs bear a highly conserved N-glycosylation site. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alopha-2,6-linked sialic acid residues. |
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