Granzyme A antibody (10R-G127A)

Mouse monoclonal Granzyme A antibody

Synonyms Monoclonal Granzyme A antibody, Anti-Granzyme A antibody
Cross Reactivity This antibody recognizes the Granzyme A antigen, which is expressed on human lymphocytes (CTL and NK-cells)
Applications User optimized
Immunogen Granzyme A antibody was raised in using recombinant granzyme A as the immunogen.

Specifications

Host Mouse
Clone GA6
Isotype IgG1
Form & Buffer Supplied as a liquid in PBS, pH 7.5.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Granzyme A is the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme A is unique among granzymes in that it is a disulfide linked homodimer. Granzyme B is thought to be a rapidly acting apoptotic enzyme, while Granzyme A is thought to be slow acting. Granzyme A is a 28 kD protein. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.

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Availability: In stock

Price: €559.81
Size: 200 ug
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