Granzyme A antibody (biotin) (61R-G120aBT)

Mouse monoclonal Granzyme A antibody (biotin)

Synonyms Monoclonal Granzyme A antibody, Anti-Granzyme A antibody
Specificity Human granzyme A
Cross Reactivity This antibody recognizes the Granzyme A antigen, which is expressed on human lymphocytes (CTL and NK-cells)
Applications ELISA
Immunogen Granzyme A antibody (biotin) was raised in mouse using human granzyme A, derived from IL-2 stimulated LAK cells as the immunogen.

Specifications

Host Mouse
Clone CLB-GA28
Isotype IgG1
Tag/Conjugate Biotin
Form & Buffer Liquid in 20mM TRIS, pH 8.0, with 150mM NaCl.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Granzyme A is the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme A is unique among granzymes in that it is a disulfide linked homodimer. Granzyme B is thought to be a rapidly acting apoptotic enzyme, while Granzyme A is thought to be slow acting. Granzyme A is a 28 kD protein. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.

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Availability: In stock

Price: €558.16
Size: 100 ug
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