GSK3a antibody (70R-11868)

Rabbit polyclonal GSK3a antibody

Synonyms Polyclonal GSK3a antibody, anti-GSK3a antibody, GSK3a, GSKa 3, GSKa 3 antibody, Glycogen synthase kinase-3 antibody, GSK-3 alpha antibody, GSK-3 alpha antibody, GSKa-3, DKFZp686D0638 antibody, GSKa-3 antibody
Cross Reactivity Human, Mouse, Rat
Applications IHC, IP, WB
Immunogen GSK3a antibody was raised in Rabbit using synthetic peptide from human GSK-3alpha as the immunogen.

Specifications

Host Rabbit
Isotype IgG
Method of Purification GSK3a antibody was purified by affinity chromatography
Form & Buffer Supplied in PBS buffer, pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide
Concentration 200 ug/ml

Usage & Assay Information

Usage Recommendations IHC: 20-30 ug/ml, WB: 1-2 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Glycogen synthase kinase 3 is a serine/threonine protein kinase that has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3alpha and Ser9 of GSK-3beta. GSK-3 has also been implicated in alzheimer’s disease. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK-3.

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Availability: In stock

Price: €306.75
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