GSKIP protein (His tag) (80R-1765)

Purified recombinant Human GSKIP protein

Synonyms GSK3-beta interaction protein, protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of GSKIP protein (His tag) (80R-1765)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-139 amino acids: MGSSHHHHHH SSGLVPRGSH METDCNPMEL SSMSGFEEGS ELNGFEGTDM KDMRLEAEAV VNDVLFAVNN MFVSKSLRCA DDVAYINVET KERNRYCLEL TEAGLKVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKRDGQS
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 17.8 kDa (159aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0. containing 1mM DTT, 10% glycerol and 50mM NaCl
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance GSKIP (GSK3 beta interaction protein) is defined as a naturally occurring protein that is homologous with the GSK3beta interaction domain of Axin and is able to negatively regulate GSK3 beta of the Wnt signaling pathway. GSKIP may affect GSK3 beta activity on neurite outgrowth by inhibiting the specific phosphorylation of tau (ser396). Recombinant human GSKIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of GSKIP protein (His tag) (80R-1765) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €239.92
Size: 100 ug
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