GSTM1 antibody (70R-13538)
Affinity purified Rabbit polyclonal GSTM1 antibody
Overview
Overview
| Synonyms | Polyclonal GSTM1 antibody, Anti-GSTM1 antibody, GSTM1b-1b antibody, glutathione S-aryltransferase antibody, GSTM1, H-B antibody, S-(hydroxyalkyl)glutathione lyase antibody, glutathione S-transferase M1 antibody, GTH4 antibody, GSTM-1 antibody, GSTM 1, MU-1 antibody, GSTM1a-1a antibody, MGC26563 antibody, HB subunit 4 antibody, glutathione S-aralkyltransferase antibody, GSTM1 antibody, GSTM1-1 antibody, GTM1 antibody, GSTM-1, MU antibody, GSTM 1 antibody, GST1 antibody |
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| Cross Reactivity | Human, Mouse |
| Applications | ICC, IF, IHC-P, WB |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | GSTM1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 21 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. |
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