GSTM1 antibody (70R-13538)

Affinity purified Rabbit polyclonal GSTM1 antibody

Synonyms Polyclonal GSTM1 antibody, Anti-GSTM1 antibody, GSTM1b-1b antibody, glutathione S-aryltransferase antibody, GSTM1, H-B antibody, S-(hydroxyalkyl)glutathione lyase antibody, glutathione S-transferase M1 antibody, GTH4 antibody, GSTM-1 antibody, GSTM 1, MU-1 antibody, GSTM1a-1a antibody, MGC26563 antibody, HB subunit 4 antibody, glutathione S-aralkyltransferase antibody, GSTM1 antibody, GSTM1-1 antibody, GTM1 antibody, GSTM-1, MU antibody, GSTM 1 antibody, GST1 antibody
Cross Reactivity Human, Mouse
Applications ICC, IF, IHC-P, WB

Images

Western blot analysis using GSTM1 antibody (70R-13538)

Western blot analysis of 50 ug of whole cell lysate (A: mouse brain) using a 12 % SDS PAGE gel and GSTM1 antibody at a dilution of 1:1000

Specifications

Host Rabbit
Isotype IgG
Method of Purification GSTM1 antibody was purified by antigen-affinity chromatography
Molecular Weight 21 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

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Images

  • <div><font face=Calibri size=2>Western blot analysis using GSTM1 antibody (70R-13538)</font></div>     | Western blot analysis of 50 ug of whole cell lysate (A: mouse brain) using a 12 % SDS PAGE gel and GSTM1 antibody at a dilution of 1:1000
  • <div><font face=Calibri size=2>Immunohistochemical staining using GSTM1 antibody (70R-13538)</font></div>     | Immunohistochemical staining of paraffin-embedded NCI-N87 xenograft using GSTM1 antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using GSTM1 antibody (70R-13538)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: Hela) using a 12 % SDS PAGE gel and GSTM1 antibody at a dilution of 1:1000
  • <div><font face=Calibri size=2>Immunofluorescent staining using GSTM1 antibody (70R-13538)</font></div>     | Immunofluorescence analysis of methanol-fixed HeLa, using GSTM1 antibody at 1:200 dilution.

Availability: In stock

Price: €323.11
Size: 100 ul
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