HAMA blocking reagent (85R-1003)

HAMA Blocking Reagent for use in immunoassays such as Rapid Tests

Synonyms Heterophilic Immunoglobulin Blocking Reagent, Rheumatoid Factor blocking reagent, RF blocking reagent, HA blocking reagent
Applications Immunoassays, Rapid Test

Specifications

Form & Buffer 10mM PBS, pH 7.4.

Usage & Assay Information

Usage Recommendations Use at 1:8-1:10; Recommended for application to double-antibody sandwich assay to eliminate the interference caused by different HA, HAMA in Rapid Tests

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Heterophilic Antibody (HA) interference in double-antibody sandwich reaction models can lead to false positive results due to non specific binding to capture and detection reagents. In particular, non specific binding of Human Anti-Mouse Antibody (HAMA) occurs in approximately 10% of immunodiagnostic assays. Other types of HA include, Heterophilic Antibody Goat Antibody (HAGA), Heterophilic Antibody Sheep Antibody (HASA), and Heterophilic Antibody Rabbit Antibody (HARA). This blocking reagent binds to the interferent HAMAs blocking its reaction with capture antibody or conjugated antibody.

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Price From: Price: €122.70

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Price From: Price: €122.70
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