HDAC6 antibody (70R-14138)

Affinity purified Rabbit polyclonal HDAC6 antibody

Synonyms Polyclonal HDAC6 antibody, anti-HDAC6 antibody, HDAC 6 antibody, HD6 antibody, HDAC 6, JM21 antibody, HDAC-6 antibody, HDAC-6 antibody, HDAC-6, histone deacetylase 6 antibody, HDAC6
Applications IHC-P, WB
Immunogen HDAC6 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human HDAC6, different from the related rat and Rabbit sequences by two amino acids, as the immunogen

Images

Western blot analysis using HDAC6 antibody (70R-14138)

Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Testis Tissue Lysate, Lane 3: HELA Cell Lysate

Specifications

Host Rabbit
Isotype IgG
Method of Purification HDAC6 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Human HDAC6 possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.

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Images

  • Western blot analysis using HDAC6 antibody (70R-14138) | Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Testis Tissue Lysate, Lane 3: HELA Cell Lysate

Availability: In stock

Price: €377.10
Size: 100 ug
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