Helicobacter pylori antibody (CagA protein) (10-7861)
Mouse monoclonal CagA protein antibody (Helicobacter pylori)
Overview
Overview
| Synonyms | Monoclonal CagA protein antibody, Anti-CagA protein antibody, Helicobacter pylori protein antibody, H. pylori protein antibody |
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| Applications | ELISA, Immunoassays, WB |
| Immunogen | Helicobacter pylori CagA protein antibody was raised in mouse using recombinant fragments of CA-gene of H pylori as the immunogen. |
Specifications
| Host | Mouse |
|---|---|
| Clone | M18612CG3 |
| Isotype | IgG |
| Method of Purification | Helicobacter pylori CagA protein antibody was purified by Protein G chromatography. |
| Form & Buffer | Supplied in PBS, pH 7.4, 0.1 % sodium azide (NaN3) |
Storage & Safety
| Storage | Store at 4 Deg C |
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| Biohazard Information | This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropria |
General Information
| Biological Significance | The cagA gene codes for one of the major H. pylori virulence proteins. Bacterial strains that have the cagA gene are associated with an ability to cause ulcers. The cagA gene codes for a relatively long (1186 amino acid) protein. The cag pathogenicity island (PAI) has about 30 genes, part of which code for a complex type IV secretion system. The low GC-content of the cag PAI relative to the rest of the Helicobacter genome suggests the island was acquired by horizontal transfer from another bacterial species. |
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