Hepatitis C Virus NS4 Genotype 1 protein (30R-AH057)

Hepatitis C Virus NS4 Mosaic Genotype-1 recombinant protein

Synonyms Hepatitis C protein, HCV protein, Hep C protein, HCV Recombinant protein, HCV NS4 Genotype 1 protein
Species Viral
Protein Type Recombinant
Applications ELISA, WB

Specifications

Residues The E.coli derived recombinant protein contains the HCV NS4 immunodominant regions, amino acids 1691-1710, 1712-1733 and 1921-1940, fused with a GST tag at N-terminus.
Expression System E.coli
Grade & Purity > 95% pure
Method of Purification Hepatitis C Virus NS4 Genotype 1 protein was purified by a proprietary chromatographic technique.
Tag/Conjugate GST tag
Form & Buffer 1.5M urea, with 25mM Tris-HCl, pH-8, 0.2% Triton-X and 50% glycerol.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price From: Price: €399.18

* Required Fields

Price From: Price: €399.18
Shipping
View Our Distributors