Hepatitis C Virus NS5 protein (30R-AH009x)
Hepatitis C Virus NS5 Genotype-1a (2322-2423) recombinant protein
Overview
Overview
| Synonyms | HCV NS5 protein, Hepatitis C protein, HCV protein, Hep C protein, HCV Recombinant protein |
|---|---|
| Species | Viral |
| Protein Type | Recombinant |
| Applications | ELISA, WB |
Specifications
| Residues | HCV NS5 immunodominant regions of Hepatitis C Virus protein containing amino acids 2322-2423. |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Method of Purification | Hepatitis C Virus NS5 protein was purified by a proprietary chromatographic technique. |
| Molecular Weight | 38.34 kDa |
| Tag/Conjugate | GST tag |
| Form & Buffer | 50mM Tris, pH 8.0, with 5mM EDTA. Please Note: Buffer may change with new Lots. |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
|---|
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|
General Information
| Biological Significance | HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product