Hepatitis D Virus protein (30R-AH055X)
Hepatitis D Virus recombinant protein
Overview
Overview
| Synonyms | Hepatitis D protein, HDV protein, Hep D protein |
|---|---|
| Species | Viral |
| Protein Type | Recombinant |
| Applications | ELISA, WB |
Specifications
| Residues | HDV immunodominant regions of the Hepatitis D Virus protein containing amino acids 1-108 and 151-209. |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 90% pure |
| Method of Purification | Hepatitis D Virus protein was purified by a proprietary chromatographic technique. |
| Form & Buffer | Liquid in 50mM Tris, pH 8with 8M urea.NOTE:BUFFER MAY CHANGE WITH NEW LOTS. Previous buffer was 10mM carbonate buffer, pH 10.0, with NaCl 100mM and 50% glycerol. |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | The HDV genome exists as a negative sense, single-stranded, closed circular RNA. Because of a nucleotide sequence that is 70% self-complementary, the HDV genome forms a partially double stranded RNA structure that is described as rod-like. With a genome of approximately 1700 nucleotides, It has been proposed that HDV may have originated from a class of plant viruses called viroids. Evidence in support of this hypothesis stems from the fact that both HDV and viroids exist as single-stranded, closed circular RNAs that have rod-like structures. Likewise, both HDV and viroids contain RNA sequences that can assume catalytically active structures called ribozymes. |
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