HER3 antibody (Tyr1222) (70R-33616)

Rabbit polyclonal HER3 antibody (Tyr1222)

Synonyms Polyclonal HER3 antibody, Anti-HER3 antibody, ERBB 3 antibody, ERBB-3 antibody, erbB3 S antibody, Glial growth factor receptor antibody, LCCS2 antibody, MDA BF 1 antibody, MGC88033 antibody, p180 ErbB3 antibody, p45 sErbB3 antibody, p85 sErbB3 antibody, proto-oncogene-like c ErbB 3 antibody, proto-oncogene-like c ErbB3 antibody, Proto-oncogene-like c-ErbB-3 antibody, receptor tyrosine kinase ERB3 [precursor] antibody, Receptor tyrosine kinase erbB 3 antibody, Receptor tyrosine kinase erbB3 antibody, Receptor tyrosine-protein kinase erbB-3 antibody, Tyrosine kinase type cell surface receptor HER3 antibody, Tyrosine kinase-type cell surface receptor HER3 antibody, V erb b2 avian erythroblastic leukemia viral oncogene homolog 3 antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 antibody, HER-3 antibody, HER 3 antibody
Specificity HER3 antibody detects endogenous levels of HER3/ErbB3 only when phosphorylated at tyrosine 1222
Cross Reactivity Mouse, Rat
Applications ELISA, IF, IHC, WB
Immunogen HER3 antibody was raised in Rabbit using synthesized phosphopeptide derived from human HER3/ErbB3 around the phosphorylation site of tyrosine 1222 (L-G-YP-E-Y) as the immunogen

Images

Immunofluorescent staining using HER3 antibody (Tyr1222) (70R-33616)

Immunofluorescence analysis of HuvEc cells, using HER3/ErbB3 (Phospho-Tyr1222) antibody.

Specifications

Host Rabbit
Isotype IgG
Residues Human: Tyr1222, Mouse: Tyr1219, Rat: Tyr1219
Form & Buffer Supplied in PBS buffer (without Mg2+and Ca2+), pH 7.4, 150mM NaCl with 0.02% sodium azide and 50% glycerol
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1000, IHC: 1:50-1:100, IF: 1:100-1:500, ELISA: 1:20000

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles

General Information

Biological Significance Elevated expression of HER3 in breast and other tumors is indicative of poor outcome.

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Images

  • Immunofluorescent staining using HER3 antibody (Tyr1222) (70R-33616) | Immunofluorescence analysis of HuvEc cells, using HER3/ErbB3 (Phospho-Tyr1222) antibody.
  • Western Blot analysis using HER3 antibody (Tyr1222) (70R-33616) | Western blot analysis of extracts from HUVEC cells, treated with EGF (200ng/ml, 30mins), using HER3/ErbB3 (Phospho-Tyr1222) antibody.

Availability: In stock

Price: €230.67
Size: 100 ug
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