HGF protein (30R-AH020)

Purified recombinant Human HGF protein

Synonyms SF protein, Scatter Factor protein, Hepatopoietin protein, Hepatocyte Growth Factor protein, HPTA protein
Species Human
Protein Type Recombinant
Applications User optimized


Expression System Hi-5 cells
Grade & Purity > 98% pure
Form & Buffer Lyophilized from 0.1M L-Arginine HCL, with 10mM tris, pH8.0 and 200mM NaCl. Reconstitute in water to a concentration of 0.5 mg/ml.

Usage & Assay Information

Bioactivity The ED50 was determined by the dose-dependent stimulation of the proliferation of monkey 4MBr-5 cells was found to be in the range of 20.0-40.0 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and Mouse HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (a-chain and beta-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer.

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Availability: In stock

Price: €185.94
Size: 10 ug
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