HGF protein (30R-AH025)
Purified recombinant Human HGF protein
Overview
Overview
| Synonyms | Scatter Factor protein, SF protein, HPTA protein, Hepatocyte Growth Factor protein, Hepatopoietin protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Expression System | Sf-9 insect cells |
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| Grade & Purity | > 95% pure |
| Molecular Weight | 78.0 kDa |
| Form & Buffer | Supplied lyophilized in 50 mM Acetic Acid. No stabilizer added. |
Storage & Safety
| Storage | Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Human Hepatocyte Growth Factor (HGF), also known as scatter factor, is a pleiotrophic cytokine that shows homology to the enzymes of the blood coagulation cascade. It stimulates the motility and invasion of several cancer cell types and can induce angiogenesis. Recently HGF was found to be identical to scatter factor, a fibroblast-derived factor promoting the dissociation of epithelial and vascular endothelial cell colonies in monolayer cell cultures by stimulating cell migration. HGF is synthesized as a biologically inactive single chain precursor, which is cleaved by a specific, extracellular serum serine protease to a fully active heterodimer. |
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