HIV1 gp120 protein (30-AH86)
Purified full length recombinant HIV1 gp120 protein-IIIB strain
Overview
Overview
| Synonyms | HIV-1 gp120 protein, HIV 1 gp120, Glycoprotein 120 protein, SU protein, HIV-1 gp120 protein, gp120 protein, gp120 protein, HIV1 gp120, gp120 glycoprotein protein, HIV 1 gp120 protein, Envelope surface glycoprotein gp120 protein, Surface protein protein, Human Immunodeficiency Virus 1 protein, HIV 1 gp120 protein, HIV-1 gp120 |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | ELISA |
Specifications
| Expression System | CHO cells |
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| Grade & Purity | > 95% pure |
| Form & Buffer | Supplied in PBS, with no preservatives. |
| Concentration | 1.0 mg/ml |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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| Bioactivity | This protein binds to human T-cell receptor CD4 in ELISA and Western ELISA as determined by CD4/gp120/Anti-gp120 mAb-peroxidase capture ELISA. This protein activates human T-Lymphocytes (CD4+, CD4-), in vitro, as measured by RNA synthesis during G0 to G1 |
Storage & Safety
| Storage | Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles |
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General Information
| Biological Significance | Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry. |
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