HIV1 gp41 antibody (20C-CR1305GP)
Goat polyclonal HIV1 gp41 antibody
Overview
Overview
| Synonyms | Polyclonal HIV1 gp41 antibody, Anti-HIV1 gp41 antibody, Env antibody, HIV1 gp41, HIV-1 gp41 antibody, Transmembrane protein antibody, GP120 antibody, TM antibody, Envelope glycoprotein gp160 antibody, Human Immunodeficiency Virus Type 1 gp41 antibody, HIV gp4 -1, gp41 antibody, HIV gp4 1, HIV 1 p41 antibody, Envelope Protein gp120 antibody, HIV gp4 1 antibody, Glycoprotein 41 antibody, HIV gp4 -1 antibody, Human Immunodeficiency Virus 1 antibody, Env polyprotein antibody |
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| Specificity | HIV-1 |
| Cross Reactivity | This antibody recognizes amino acid residues 546-682 of strain HxB2 |
| Applications | ELISA, IHC, WB |
| Immunogen | HIV1 gp41 antibody was raised in goat using recombinant ectodomain of gp41 as the immunogen. |
Specifications
| Host | Goat |
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| Grade & Purity | > 95% pure |
| Form & Buffer | 10mM PBS, pH 7.2, with 0.1% NaN3. |
| Concentration | Typically 4-5 mg/ml |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | gp41 is a glycoprotein subunit that remains non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4, gp120 changes its conformation, causing gp41 to become exposed, where it can assist in fusion with the host cell. |
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