HIV1, HxB2, HxB3 rev antibody (FITC) (61-006103)

Mouse monoclonal REV (HIV-1 HxB2, HxB3) antibody (FITC)

Synonyms Monoclonal REV (HIV-1 HxB2, HxB3) antibody, HIV-1, HIV1, HIV 1, HIV-1 antibody, HIV 1 antibody, HxB3) antibody, Anti REV (HIV-1 HxB2
Specificity HIV1
Applications ELISA, WB
Immunogen HIV1, HxB2, HxB3 Rev antibody was raised in mouse using purified, full length rev (HIV-1 HxB2, HxB3) produced in E.coli Expression system as the immunogen.
Assay Information Binds to recombinant rev (HIV-1 HxB2, HxB3) in ELISA and Western Blot. The antibody is epitope mapped to rev (70-84)

Specifications

Host Mouse
Clone 9G2G4D6E8
Isotype IgG2b
Tag/Conjugate FITC
Form & Buffer Supplied liquid as a purified IgG in PBS buffer, with no preservatives added.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:500-1:1000, WB: 1:500-1:1000

Storage & Safety

Storage Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles
Biohazard Information Not tested for sterility or endotoxin content.

General Information

Biological Significance Rev is a HIV gene. The name rev stands for "Regulator of Virion". The gene's protein product allows fragments of HIV mRNA that contain a Rev Response Element (RRE) to be exported from the nucleus to the cytoplasm. In the absence of the rev gene, the host RNA splicing machinery in the nucleus quickly splices the RNA so that only the smaller, regulatory proteins can be produced; in the presence of rev, RNA is exported from the nucleus before it can be spliced, so that the structural proteins and RNA genome can be produced.

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Availability: In stock

Price From: Price: €77.71
Price From: Price: €77.71
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