Polyclonal HIV-1 p17 antibody, Anti-HIV-1 p17 antibody, MA protein, HIV1 matrix protein p17 antibody, Human Immunodeficiency Virus 1 antibody, p17 antibody, HIV 1 p17 antibody, Matrix protein p17 antibody, Anti Human Immunodeficiency Virus 1 antibody
Specificity
HIV1 p17
Applications
ELISA, WB
Immunogen
HIV1 p17 antibody was raised in goat using recombinant p17 as the immunogen.
Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles
General Information
Biological Significance
The p17 matrix protein, one of the products of the HIV gag gene, serves a structural function inside mature HIV particles. Units of p17 line the inside of the HIV envelope, helping to anchor the gp41/gp120 "spikes" to the envelope. Once the HIV core has entered the cell, p17 also serves the function of helping it be transferred into the cell's nucleus. It achieves this because it carries "nuclear localisation signals" (sequences of protein which are recognised by cellular machinery as indicating that it should be transported into the nucleus).