HIV1 protease IIIB protein (30-031001)
Purified HIV1 protease IIIB protein
Overview
Overview
| Synonyms | HIV1 Protease IIIB protein, HIV 1 Protease IIIB protein, HIV-1 Protease IIIB protein, HIV-1 Protease IIIB protein, Human Immunodeficiency virus Type 1 protease IIIB protein, HIV-1 Protease IIIB, HIV1 Protease IIIB, HIV 1 Protease IIIB |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | User optimized |
Storage & Safety
| Storage | Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles |
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General Information
| Biological Significance | HIV-1 protease (HIV PR) is a retroviral aspartyl protease that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV PR cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV PR, HIV virions remain uninfectious. Thus, mutation of HIV PR’s active site or inhibition of its activity disrupts HIV’s ability to replicate and infect additional cells, making HIV PR inhibition the subject of much pharmaceutical research. |
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