Monoclonal HIV1 Rev antibody, Anti-HIV1 Rev antibody, art/trs antibody, HIV1gp6 antibody, Regulator of expression of viral proteins antibody, Anti repression transactivator protein antibody, Human immunodeficiency virus 1 Rev antibody, HIV Rev-1 antibody, Rev antibody, HIV Rev 1, Protein Rev antibody, HIV Rev 1 antibody, HIV Rev-1, HIV1 Rev
Specificity
HIV1 Rev
Cross Reactivity
This antibody binds to recombinant rev (HIV1, HxB2, HxB3) in ELISA and Western Blot
Applications
ELISA, WB
Immunogen
HIV1 Rev antibody was purified in mouse using recombinant Rev (HIV-1, HxB2, HxB3) as the immunogen.
Assay Information
Binds to recombinant rev (HIV-1, HxB2, HxB3) in ELISA and Western Blot
Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles
Biohazard Information
Not tested for sterility or endotoxin content.
General Information
Biological Significance
Rev is a HIV gene. The name rev stands for "Regulator of Virion". The gene's protein product allows fragments of HIV mRNA that contain a Rev Response Element (RRE) to be exported from the nucleus to the cytoplasm. In the absence of the rev gene, the host RNA splicing machinery in the nucleus quickly splices the RNA so that only the smaller, regulatory proteins can be produced; in the presence of rev, RNA is exported from the nucleus before it can be spliced, so that the structural proteins and RNA genome can be produced.