Polyclonal HIV1 rev antibody, Anti-HIV1 rev antibody, Anti repression transactivator protein antibody, art/trs antibody, HIV rev 1 antibody, HIV1gp6 antibody, Regulator of expression of viral proteins antibody, HIV1 rev, HIV rev 1, HIV rev-1, Human immunodeficiency virus 1 Rev antibody, Rev antibody, HIV rev-1 antibody, Protein Rev antibody
Specificity
HIV-1 Rev
Cross Reactivity
To be determined by end-user
Applications
ELISA, WB
Immunogen
HIV1 rev antibody (FITC) was raised in rabbit using full length recombinant rev (HIV-1, HxB2, HxB3) produced in E. coli expression system as the immunogen.
Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Rev is a HIV gene. The gene's protein product allows fragments of HIV mRNA that contain a Rev Response Element (RRE) to be exported from the nucleus to the cytoplasm. In the absence of the rev gene, the host RNA splicing machinery in the nucleus quickly splices the RNA so that only the smaller, regulatory proteins can be produced; in the presence of rev, RNA is exported from the nucleus before it can be spliced, so that the structural proteins and RNA genome can be produced.