HIV1-RT protein (30-026001)
Purified recombinant HIV1-RT protein
Overview
Overview
| Synonyms | HIV-1 RT, HIV 1-RT, HIV-1 RT protein, HIV1RT protein, HIV1 RT protein, HIV 1-RT protein, HIV-1 Reverse Transcriptase protein, HIV1-RT |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Expression System | E.coli |
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| Form & Buffer | Supplied lyophilized from PBS buffer, with no preservatives added, reconstitute in sterile distilled water. |
Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | HIV1 Reverse Transcriptase is an RNA-dependent DNA polymerase of HIV1 (AIDS virus), subtype B origin. It is responsible for the production of a double stranded DNA copy of the single stranded RNA genome that is contained in the HIV1 virus particle and primed by the host cell lysine-tRNA which partly unfolds and anneals to the 5' end of the viral genomic RNA. This is extended by the polymerase function of RT to give a DNA-RNA hybrid. It also has RNaseH activity which degrades the RNA component of this hybrid once it has been copied. |
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